abstract：PURPOSE:We have previously reported that mouse kallikrein (KLK) 22 in the lacrimal and salivary glands is an autoantigen that can induce primary Sjogren syndrome (SS) in rats. In this study, we determine whether the production of antibodies against tissue KLK is specific for SS and whether the antibody can be used as a...

journal_title：Cornea

authors： El Annan J,Jiang G,Wang D,Zhou J,Foulks GN,Shao H

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To address the effect of topical instillation of oxybuprocaine on the relative distribution of corneal thickness (CT) in young healthy subjects. METHODS:Prospective study involving 30 eyes of 30 emmetropic subjects (24 ± 3 years). Corneal thickness measurements were carried out before and 3 minutes after the i...

journal_title：Cornea

authors： Sanchis-Gimeno JA,Palanca-Sanfrancisco JM,García-Lázaro S,Madrid-Costa D,Cerviño A

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To compare efficiency and safety of epithelium-off corneal cross-linking (CXL) and transepithelial cross-linking (TE-CXL) in pediatric patients with progressive keratoconus. METHODS:Uncorrected and corrected visual acuity, corneal topography and pachymetry (Pentacam; Oculus Pentacam), and in vivo confocal micr...

journal_title：Cornea

authors： Magli A,Forte R,Tortori A,Capasso L,Marsico G,Piozzi E

更新日期：2013-05-01 00:00:00

abstract：PURPOSE:To report clinical experience with the use of voriconazole for management of cases with fungal keratitis and to evaluate the factors affecting treatment outcomes. METHODS:Retrospective database review of all cases with fungal keratitis that were treated with topical voriconazole at the Royal Victorian Eye and ...

journal_title：Cornea

authors： Ramakrishnan T,Constantinou M,Jhanji V,Vajpayee RB

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To examine the validity of the observations made by specialist corneal surgeons that there seems to be an absence or loss of older patients with keratoconus (KC). METHODS:Using a PubMed search and key words such as KC, epidemiology, mortality, mitral valve prolapse, atopy, and asthma, the literature related to...

journal_title：Cornea

authors： McMonnies CW

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:We standardized quality-controlled cord blood serum (CBS)-based eye drops and evaluated the efficacy of 1-month CBS treatment in the healing of diseased corneal epithelium in severe dry eye (DE) patients. METHODS:Seventeen graft-versus-host disease (GVHD) and 13 Sjogren syndrome patients with severe persistent...

journal_title：Cornea

authors： Versura P,Profazio V,Buzzi M,Stancari A,Arpinati M,Malavolta N,Campos EC

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To assess the use of serial computed tomography (CT) in the detection of osteo-odonto-lamina resorption in osteo-odonto-keratoprosthesis (OOKP) and to investigate the use of new volumetric software, Advanced Lung Analysis software (3D-ALA; GE Healthcare), for detecting changes in OOKP laminar volume. METHODS:A...

journal_title：Cornea

authors： Sipkova Z,Lam FC,Francis I,Herold J,Liu C

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Ocular injuries after exposure to the vesicant sulfur mustard (SM) are characterized by acute corneal erosions and inflammation of the anterior segment that may be followed by delayed limbal stem cell deficiency (LSCD), expressed clinically by corneal neovascularization and epithelial defects. The present study...

journal_title：Cornea

authors： Kadar T,Dachir S,Cohen M,Gutman H,Cohen L,Brandeis R,Horwitz V,Amir A

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:To determine the effects of single radial or horizontal suture placement in 2-step clear corneal incision (CCI) wound apposition and permeability to particles of India ink. METHODS:Five fresh human globes were included. Two 25-gauge needles connected to a saline solution bag and to a digital manometer were ins...

journal_title：Cornea

authors： May WN,Castro-Combs J,Kashiwabuchi RT,Tattiyakul W,Qureshi-Said S,Hirai F,Behrens A

更新日期：2013-03-01 00:00:00

abstract：PURPOSE:To evaluate the efficacy of corneal cross-linking (CXL; riboflavin/ultraviolet A) as a simple therapy for Acanthamoeba keratitis. METHODS:Twenty rabbits were systemically anesthetized and the stroma of their right corneas was inoculated with a suspension of Acanthamoeba. Rabbits were divided into 2 groups: one...

journal_title：Cornea

authors： Berra M,Galperín G,Boscaro G,Zarate J,Tau J,Chiaradia P,Berra A

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To evaluate the results of a combined approach of cicatrix lysis, intraoperative mitomycin C (MMC) application, oral mucosal transplantation (OMT), and amniotic membrane transplantation (AMT) for surgery of severe symblepharon. METHODS:This prospective study included 32 eyes with severe symblepharon in which a...

journal_title：Cornea

authors： Kheirkhah A,Ghaffari R,Kaghazkanani R,Hashemi H,Behrouz MJ,Raju VK

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:Microbiological contamination is a common cause for elimination of organ-cultured donor corneas. The aims of the present study were to analyze contamination rates and identify risk factors for contamination. METHODS:Retrospectively, the contamination rates of 4546 organ-cultured corneas and the causative speci...

journal_title：Cornea

authors： Linke SJ,Fricke OH,Eddy MT,Bednarz J,Druchkiv V,Kaulfers PM,Wulff B,Püschel K,Richard G,Hellwinkel OJ

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To evaluate the prevalence of positive microbiology results (culture and/or Gram stain) in donor cornea tissue with newer transplant methods and to assess if the results subsequently correlate with higher incidence of clinical infection. METHODS:A retrospective review of the microbiology records of 569 consecu...

journal_title：Cornea

authors： Garg S,Said B,Farid M,Steinert RF

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:The depth of corneal crosslinking (CXL) does not seem homogeneous within the treatment area but shows a reduction toward the periphery of the cornea. This study was undertaken to investigate this reduction effect and to look for possible solutions. METHODS:Ten corneas were investigated by means of an optical c...

journal_title：Cornea

authors： Koller T,Schumacher S,Fankhauser F 2nd,Seiler T

更新日期：2013-02-01 00:00:00

abstract：PURPOSE:To present a novel noncontact meibography system with anterior segment optical coherence tomography (OCT), which is widely used in clinics for the anterior segment (cornea, anterior chamber angle, etc.), and compare the results with preexisting infrared meibography. METHODS:This research was carried out at the...

journal_title：Cornea

authors： Hwang HS,Park CW,Joo CK

更新日期：2013-01-01 00:00:00

abstract：PURPOSE:To compare the efficacy of topical cyclosporine [0.05% cyclosporine A (CsA)] and preservative-free artificial tears in the treatment of meibomian gland dysfunction (MGD). METHODS:A 3-month prospective, randomized, double-masked, parallel-group controlled trial enrolled 70 patients with symptomatic MGD and unst...

journal_title：Cornea

authors： Prabhasawat P,Tesavibul N,Mahawong W

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To investigate the effects of pterygium excision with conjunctival autograft plus corneal polishing on ocular higher-order aberrations (HOAs) and to monitor the changes throughout the first postoperative year. METHODS:A total of 18 eyes of 16 patients with primary pterygium who had an indication for surgical e...

journal_title：Cornea

authors： Gumus K,Topaktas D,Göktaş A,Karakucuk S,Oner A,Mirza GE

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:Meta-analysis to compare pterygium surgery outcomes using limbal conjunctival autograft (LCAG) and other techniques. METHODS:A comprehensive literature search was conducted through June 2011 using PubMed, Embase, and the Cochrane Registry to identify all randomized control trials reported so far, comparing the...

journal_title：Cornea

authors： Zheng K,Cai J,Jhanji V,Chen H

更新日期：2012-12-01 00:00:00

abstract：PURPOSE:To investigate the efficacy of a topical anti-tumor necrosis factor-α agent, infliximab, in a mouse model of experimental dry eye (EDE). METHODS:EDE was induced in C57BL/6 mice, with or without topical treatment consisting of balanced salt solution or 0.001%, 0.01%, or 0.1% infliximab solutions. Tear volume an...

journal_title：Cornea

authors： Li Z,Choi W,Oh HJ,Yoon KC

更新日期：2012-11-01 00:00:00

abstract：:The introduction of the excimer laser for keratorefractive surgery in the 1990 s permanently reshaped the treatment landscape for correcting refractive errors, such as myopia, hyperopia, and astigmatism. Until that point, these treatments had relied on less predictable techniques, such as radial keratotomy and automat...

journal_title：Cornea

authors： Azar DT,Chang JH,Han KY

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To evaluate the prevalence of undiagnosed and asymptomatic human immunodeficiency virus (HIV) infection in patients with ocular surface squamous neoplasia (OSSN) in a referral hospital in Karnataka, South India. METHODS:A consecutive series of patients presenting with OSSN were evaluated in an academic center ...

journal_title：Cornea

authors： Pradeep TG,Gangasagara SB,Subbaramaiah GB,Suresh MB,Gangashettappa N,Durgappa R

更新日期：2012-11-01 00:00:00

abstract：PURPOSE:To evaluate the changes and trends in the number and characteristics of contact lens-related ulcers (CLRUs) and to compare the results with those of previously published series at our institution. METHODS:Medical records of all patients diagnosed with presumed bacterial corneal ulcers seen at the Cornea Servic...

journal_title：Cornea

authors： Yildiz EH,Airiani S,Hammersmith KM,Rapuano CJ,Laibson PR,Virdi AS,Hongyok T,Cohen EJ

更新日期：2012-10-01 00:00:00

abstract：PURPOSE:Evaluation of efficacy of autologous platelet-rich plasma eyedrops as an adjunct to standard medical treatment as compared with standard medical treatment with artificial tears in acute ocular chemical injury. METHODS:Twenty eyes with grade III to grade V chemical injury were randomly assigned to 2 groups. Gro...

journal_title：Cornea

authors： Panda A,Jain M,Vanathi M,Velpandian T,Khokhar S,Dada T

更新日期：2012-09-01 00:00:00

abstract：:To evaluate an innovative technique for intrastromal air injection to achieve deep anterior lamellar keratoplasty (DALK) with bare Descemet membrane (DM). Thirty-four eyes with anterior corneal pathology, including 27 with keratoconus, underwent DALK. After 400 μm trephination with a suction trephine, ultrasound pachy...

journal_title：Cornea

authors： Ghanem RC,Ghanem MA

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:To evaluate tear film osmolarity in patients treated with intraocular pressure-lowering medications. METHODS:Forty patients treated for glaucoma or ocular hypertension (OHT) were consecutively recruited for the study. Each patient was asked to complete an evaluation of ocular surface disease symptoms, the Ocul...

journal_title：Cornea

authors： Labbé A,Terry O,Brasnu E,Van Went C,Baudouin C

更新日期：2012-09-01 00:00:00

abstract：PURPOSE:The 27-kDa heat shock protein (HSP27) has been implicated in wound healing in multiple tissues. We investigated the expression and localization of phosphorylated HSP27 during epithelial wound healing in the murine cornea. METHODS:Corneas of 8- to 10-week-old C57BL6 mice were wounded by epithelial debridement (...

journal_title：Cornea

authors： Jain S,De la Cruz J,Kang E,Kojima T,Chang JH,Kim JY

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To measure the refractive index (RI) of the human corneal stroma in vivo using an objective Abbé refractometer (VCH-1) and to determine if RI of the stroma is related to age. METHODS:VCH-1 was used to measure RI at the central anterior stroma immediately after lifting the flap in neophyte patients preselected ...

journal_title：Cornea

authors： Amparo F,Patel S,Alió JL,Rodriguez-Prats JL,Moreno LJ

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:One of the most disturbing trends in recent years is the growth of resistant strains of bacteria with the simultaneous dearth of new antimicrobial agents. Thus, new antimicrobial agents for the use on the ocular surface are needed. METHODS:We synthesized a variety of ionic liquid compounds, which possess 2 pos...

journal_title：Cornea

authors： O'Toole GA,Wathier M,Zegans ME,Shanks RM,Kowalski R,Grinstaff MW

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:To report the first use of Descemet stripping automated endothelial keratoplasty (DSAEK) for spontaneous Descemet membrane detachment in a patient with osteogenesis imperfecta (OI), keratoconus, and acute bullous keratopathy. METHODS:A case report of a 25-year-old man with OI and symptomatic unilateral bullous...

journal_title：Cornea

authors： Gorovoy MS,Gorovoy IR,Ullman S,Gorovoy JB

更新日期：2012-07-01 00:00:00

abstract：PURPOSE:The etiology of keratoconus has been the subject of numerous studies. Here, we review the body of literature that attempts to determine what causes keratoconus. METHODS:A review of the published literature was performed to evaluate the possible causes of keratoconus and how the different etiologies may play a ...

journal_title：Cornea

authors： Sugar J,Macsai MS

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate outcomes of endothelial keratoplasty (EK) without Descemet membrane stripping for treatment of failed penetrating keratoplasty (PKP). METHODS:Retrospective cohort study of all eyes that underwent EK without Descemet membrane stripping for failed PKP at one institution between May 2008 and June 2010...

journal_title：Cornea

authors： Heitor de Paula F,Kamyar R,Shtein RM,Sugar A,Mian SI

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To describe the clinical results of Pentacam-based big bubble deep anterior lamellar keratoplasty (DALK) to achieve an intended 90% depth of initial lamellar trephination. METHODS:Fifty consecutive eyes of 50 patients with keratoconus, keratoglobus, and anterior stromal scars were included. DALK was performed ...

journal_title：Cornea

authors： Riss S,Heindl LM,Bachmann BO,Kruse FE,Cursiefen C

更新日期：2012-06-01 00:00:00

abstract：PURPOSE:To evaluate trends in the acquisition, storage, and utilization of donated corneal tissue in New Zealand, 2000 to 2009. METHODS:The New Zealand National Eye Bank records were analyzed for the decade January 2000 to December 2009. Variables analyzed included donor demographics (age, sex, and ethnicity), donor s...

journal_title：Cornea

authors： Cunningham WJ,Moffatt SL,Brookes NH,Twohill HC,Pendergrast DG,Stewart JM,McGhee CN

更新日期：2012-05-01 00:00:00

abstract：PURPOSE:To investigate the severity of keratoconus in terms of corneal elevation differences with 2 different reference surfaces using topographic analysis. METHODS:Eighty-six eyes of 50 patients with keratoconus of various clinical stages (61 male and 25 female eyes) with mean age of 37.3 ± 11.6 years were evaluated....

journal_title：Cornea

authors： Ishii R,Kamiya K,Igarashi A,Shimizu K,Utsumi Y,Kumanomido T

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:The significance of ocular or corneal aberrations may be subject to misinterpretation whenever eyes with different pupil sizes or the application of different Zernike expansion orders are compared. A method is shown that uses simple mathematical interpolation techniques based on normal data to rapidly determine...

journal_title：Cornea

authors： Smolek MK

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:Intrastromal corneal ring segments (ICRSs) are small arc-like implants that are being used increasingly as a minimally invasive treatment for patients with keratoconus. This study assessed the effectiveness of KeraRing implants, a type of ICRS, to treat keratoconus. METHODS:Retrospective case series descriptiv...

journal_title：Cornea

authors： Gharaibeh AM,Muhsen SM,AbuKhader IB,Ababneh OH,Abu-Ameerh MA,Albdour MD

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:To investigate the efficacy and safety of subconjunctival bevacizumab injection for the treatment of impending recurrent pterygium. METHODS:A prospective, randomized, single-masked, controlled trial was conducted in 80 patients with impending recurrent pterygium. Patients were randomized into 4 groups using ra...

journal_title：Cornea

authors： Lekhanont K,Patarakittam T,Thongphiew P,Suwan-apichon O,Hanutsaha P

更新日期：2012-02-01 00:00:00

abstract：PURPOSE:We characterized the presence of hemangiogenesis (HA) and lymphangiogenesis (LA) in human corneal specimens exhibiting 13 underlying pathologies. METHODS:Human corneal specimens were obtained from consenting subjects (n = 2 or n = 3 for each pathology; total sample size, n = 35). The pathological specimens wer...

journal_title：Cornea

authors： Tshionyi M,Shay E,Lunde E,Lin A,Han KY,Jain S,Chang JH,Azar DT

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To investigate the in vivo, corneal, biomechanical changes after corneal collagen cross-linking (CXL) using the Ocular Response Analyzer (ORA) in patients with keratoconus and post-laser in situ keratomileusis (LASIK) ectasia. METHODS:Single-center, prospective, randomized, controlled, clinical trial. After CX...

journal_title：Cornea

authors： Greenstein SA,Fry KL,Hersh PS

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:To evaluate and compare corneal higher-order aberrations (HOAs) after Descemet stripping automated endothelial keratoplasty (DSAEK), femtosecond laser-assisted penetrating keratoplasty (FLAK), and conventional penetrating keratoplasty (PKP). METHODS:A retrospective comparison of consecutive surgical series of ...

journal_title：Cornea

authors： Chamberlain W,Omid N,Lin A,Farid M,Gaster RN,Steinert RF

更新日期：2012-01-01 00:00:00